Hyperbaric Oxygen Therapy Research & News

Hyperbaric Oxygen Therapy Ailments

Here you’ll find links to some of the latest research, studies and news on Hyperbaric Oxygen Therapy and the use of Hyperbaric Chambers.

Hyperbaric Low-pressure air increases stem cell mobilization by 2–3 times.

Stem cells are mobilized when inhaling air (21% oxygen) at 1.3 ATA of hyperbaric pressure, according to a recent groundbreaking study in hyperabric medicine (HBOT). HBOT has been known to speed up tissue repair and regeneration since 2006 by encouraging the release of stem cells from the bone marrow. We were unaware of the pressure level at which this occurs. So a research team made the decision to investigate, and they reported their findings in this paper. They discovered that stem cells significantly increased at a minimum pressure of 1.3 ATA. Additionally, because extra oxygen was not added to a breathing equipment during the investigation, the results were solely dependent on pressure. This groundbreaking study unequivocally shows that pressure alone can contribute to some of the astonishing advantages of hyperabric oxygen therapy that have been described. More significantly, it demonstrates that these perhaps beneficial effects may be attained at lower pressures and without the need of additional oxygen Read Article

Patients with breast cancer-related lymphedema benefit from hyperbaric oxygen in terms of quality of life.

Following breast cancer therapy, lymphedema is a frequent consequence that has a detrimental impact on quality of life (QOL). In this study, 40 sessions of hyperbaric oxygen therapy were provided over a 2-month period to 19 women who had lymphedema 1 year after receiving breast cancer treatment. They then checked in with these women again six months later to see if their quality of life had changed. The participants reported considerable QOL improvements, and the results looked good. Physical functioning, exhaustion, insomnia, and symptoms in the breast and arms were some of these improvements. improvements reaching their apex at the 6-month follow-up.
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Not Just for Health & Healing: Hyperbaric Chamber Celebrities Embrace the Benefits of Oxygen Therapy for Wellness & Recovery

Celebrity athletes are always the first to try out new ways of healing before most others. Indeed Tiger Woods was reported to have used a Hyperbaric Oxygen Therapy Chamber to aid his recovery from a number of injuries, as far back as 2010.

And more recently Neymar Jr. was was pictured in a post on Instagram inside a chamber during his recovery from a foot injury. So which celebrities are potentially benefiting from the use of oxygen therapy in Hyperbaric Chambers? The following is just a short list of some of them we know about…

Tiger Woods
LeBron James
Michael Phelps
Justin Bieber
Christiano Ronaldo
Mohamed Salah
Madonna
Leann Rimes

Beyonce
Jay Leno
Donnie Wahlberg
Usher
Jenny McCarthy
Michael Jackson
Stephen Bowden
Neymar Jr.

Hyperbaric chambers create an environment with a high oxygen content at pressures higher than those of the atmosphere. They are frequently utilised in both medical and non-medical contexts and offer a number of therapeutic advantages.

How Hyperbaric Chamber Celebrities Might Benefit:

The following are a few examples of hyperbaric chamber celebrities use for the therapy:

Improved oxygen delivery: A higher concentration of oxygen can dissolve in the bloodstream thanks to the celebrities’ hyperbaric chamber higher atmospheric pressure. This results in improved oxygen supply to tissues and organs, which promotes recovery and healing.
Tissue repair and regeneration: Hyperbaric oxygen treatment (HBOT) encourages tissue regeneration by stimulating the creation of new blood vessels (angiogenesis). Wounds, ulcers, and injuries—including those brought on by radiation therapy—can all heal more quickly.
Lessened inflammation: HBOT can aid in a number of illnesses to lessen inflammation. It modifies the function of immune cells, lowers the level of molecules that cause inflammation, and encourages the release of anti-inflammatory agents.
Better infection prevention: The hyperbaric chamber’s high oxygen content makes it difficult for some germs to grow and increases the efficiency of medications. HBOT can help treat infections, especially those brought on by non-healing wounds and impaired blood flow.
Decompression sickness treatment: Decompression sickness, which can happen to scuba divers when ascending too quickly, is primarily treated in hyperbaric therapy chambers. The elevated pressure in the chamber aids in the body’s excess nitrogen elimination and symptom reduction.
Neurological Disorders: Traumatic brain injuries, strokes, and neurodevelopmental abnormalities are among the neurological ailments for which hyperbaric therapy chambers have shown promise. The improved neuronal regeneration, less edoema, and improved brain function could all be a result of the enhanced oxygen flow.
Hyperbaric chambers are sometimes used by athletes to improve their performance and hasten recovery. The improved availability of oxygen can speed up muscle recovery, lessen tiredness, and improve athletic performance.

It’s crucial to remember that hyperbaric chamber therapy need to be applied under the supervision or guidance of qualified experts. Depending on the patient and the condition being treated, hyperbaric therapy chambers may have different unique advantages and uses.

Natural killer cells are boosted by mild hyperbaric oxygen therapy.

An essential component of the innate immune system, natural killer cells (NK) can locate, hunt down, and naturally eliminate cancer cells! 16 healthy young women participated in this crossover randomized control experiment to examine the impact of mild hyperbaric oxygen therapy (m-HBOT) on natural killer (NK) cells. According to the findings, m-HBOT at 1.4 ATA efficiently increased NK cells by controlling parasympathetic activity.
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Veterans with PTSD benefit from hyperbaric oxygen therapy.

Following their return from active duty, many veterans experience PTSD. There are currently few treatments available, and the long-term effects could be disastrous for these people. Previous studies have shown that hyperbaric oxygen therapy (HBOT) can ameliorate the clinical symptoms of PTSD in veterans by inducing neuroplasticity. In this study, 22 soldiers with PTSD were evaluated by the researchers. After completing a full course of hyperbaric oxygen therapy, these veterans underwent another evaluation one or more years later. Improvements in a number of clinical symptoms that can enhance quality of life were seen in the follow-up assessments.
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Hyperbaric oxygen treatment to the rescue for perioperative peripheral nerve damage

There are few therapy options for peripheral nerve damage, an infrequent but potentially fatal side effect of anesthesia and surgery. The literature on the use of hyperbaric oxygen therapy to treat peripheral nerve damage in humans and animals was reviewed by the study’s authors. Overall, 88% (45/51) of the included investigations (80% of human studies and 90% of animal studies) reported that hyperbaric oxygen therapy was effective, enhancing neuron regeneration and/or time to recovery with no serious side events reported.
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Overactive bladder syndrome may now be treated with hyperbaric oxygen therapy.

Urgeness, frequent urination, and nocturia are some of the signs and symptoms of overactive bladder (OAB), which is typically accompanied by urine incontinence. This study demonstrated positive outcomes from the use of hyperbaric oxygen therapy. Researchers came to the conclusion that HBOT might be a fresh method of treating overactive bladder syndrome.
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Case Report: Hyperbaric oxygen treatment used to treat a cosmetic filler injection complication

The patient received 14 sessions of hyperbaric oxygen therapy starting five days after experiencing vascular impairment as a result of a cosmetic filler operation. The patient made a nearly full recovery despite the delay in treatment, and hyperbaric oxygen therapy was generally well-tolerated.

Case Report: Telomere length and cognitive function were both improved by hyperbaric oxygen therapy

The author of this case report subjected himself to a 3-month hyperbaric treatment, which included 60 sessions. He claimed that after performing this easy treatment, his cognition, memory, brain processing speed, and athletic prowess all improved. According to additional reports, telomere length has increased.
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Hyperbaric oxygen therapy for inflammatory endometrial lesions

Endometriosis is an inflammatory condition that depends on estrogen. The anti-inflammatory effects of 10 sessions of HBOT at 2.4 ATA in mice were examined since hyperbaric oxygen treatment (HBOT) has a potent anti-inflammatory effect on the body. The outcomes showed a significant decrease in inflammatory endometrial lesions.
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A 25-year-old US Professional Football player's rehabilitation from a spinal cord injury sustained while tackling included hyperbaric oxygen therapy.

Spine injuries from football are more common and severe than previously assumed, especially in children and adolescents aged 10 to 19. Here, a 25-year-old male NFL professional player suffered a T8 American Spinal Injury Association Impairment Scale grade A catastrophic thoracic spinal cord injury after tackling. Surgery had to be done right away. After the successful surgery, a 27-day course of 30 hyperbaric oxygen therapy (HBOT) sessions at 2.4 ATA began just two days afterwards. Within this treatment, steroid therapy, hypothermia therapy, omega 3 fatty acid therapy, and HBOT were also used. This athlete was able to recover from a very bad condition because to this "aggressive medical and surgical intervention with intensive rehabilitation" and assist him restore motor function so that he could “run and jump” with “minimal spasticity.”
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Jay Leno Undergoes Intensive Hyperbaric therapy.

After undergoing surgery for severe burns to his face and hands from a gasoline accident, Jay Leno was still in the hospital on Friday.

The incident happened after a gasoline fire broke out over the weekend in the famed comedian and “Tonight Show” host’s garage. A clogged fuel line burst while he was working on his automobile, spilling fuel in his face and igniting it with a nearby spark.

– USA Today

Research - Hyperbaric Dosages

The body receives more oxygen than usual through the simple and non-invasive method known as hyperbaric oxygen therapy. The delivery method employs a hyperbaric chamber, often known as a “pressure vessel,” in which the body is subjected to varying pressures.

The pressure that is provided directly affects the oxygen dosage, so the higher the pressure, the higher the dosage of oxygen.

The amount of time and oxygen being breathed in can also be used to modify the effective dose of oxygen (during HBOT). The frequency of application is the last component of this puzzle. But once more, the pressure is the crucial factor, therefore let’s first explain:

Pressure

- We need a consistent and continuous supply of oxygen, and the ‘natural process’ of breathing provides us with this essential ingredient. During this phase, oxygen enters the lungs deeply before exiting the lung tissue and entering the bloodstream.
  - The bulk of oxygen (around 98.5%) in the bloodstream is then strongly bonded to red blood cells, and by the time these cells exit the lungs, they are essentially at their maximum oxygen carrying capability. The circulatory system is subsequently used to carry the oxygen until it reaches the metabolically active tissue. They now loosen their tight bond, allowing oxygen to diffuse into the nearby tissue. A red blood cell can hold up to one million of these oxygen molecules, however keep in mind that they are minuscule in comparison to the red blood cell that they are travelling on.
  - Only a little fraction of oxygen, about 1.5%, can leave the lung tissue and enter directly into the blood plasma (the liquid part of the blood), where it can move about freely and quickly without being constrained by being tightly linked to these red blood cells. Our huge red blood cells (roughly speaking) cannot reach places where the oxygen that passes in this compartment can reach. Therefore, when dealing with damaged tissue and/or circulatory issues, the plasma oxygen levels might be quite essential.
  - Only 0.3 ml per 100 ml of oxygen can be transported in human blood plasma under typical air circumstances. This amount is far below what is required to maintain life.
  - As a result of the oxygen molecules’ increased force under hyperbaric pressure, more oxygen can leave the lungs and move through the blood plasma. Therefore, in addition to receiving more oxygen, you are also receiving more oxygen that can readily move through blood fluids and reach every area of tissue that is encircled by fluids – essentially everywhere inside the body! This is almost ‘genuine’ liquid oxygen.
- A person who lives at sea level is at one atmosphere of absolute air pressure (ATA), which is how hyperbaric pressure is commonly measured. In terms of air pressure, this is equivalent to 760 mm (or 29.9 inches) of mercury or 14.7 psi (pounds per square inch).
  - When discussing HBOT, we begin at 1.0 ATA, which corresponds to the average air pressure at sea level. We are basically adding another atmospheric of pressure, or 14.7 psi, for every 33 FSW (feet of sea water) of pressure. As a result, if a 2.0 ATA hyperbaric pressure is provided, this pressure dosage is 14.7 psi or 33 FSW.
  - In both private facilities and wound care clinics, hyperbaric pressures are typically less than 2.5 ATA.

2. Time

HBOT sessions are typically limited to 60 to 90 minutes. This lessens the chance of the body accumulating too much oxygen, adding to the astounding safety records displayed by the facilities providing this service.

3. The Oxygen Content

In general, hyperbaric oxygen entails breathing oxygen concentrations that are greater than normal, all the way up to 100% oxygen. We are currently breathing air that contains only 21% oxygen. Remember that in a hyperbaric chamber, breathing ordinary air will still allow for the delivery of extra oxygen to the body.

4. The Regularity of Deliveries

Many of the physiological advantages of HBOT can be attained with the aid of frequent delivery, which can play a significant role. When using this approach to manage wound care or even in cases of chronic disorders, this is of utmost relevance. The “40 hour hyperbaric protocol” is a fairly popular procedure that has been found to provide these physiological effects. Pressure (from 1.3 ATA to 2.4 ATA) and time (from 60 to 90 minutes) for this treatment have been adjusted. You can see 1.3 ATA for 60 minutes on one end of the range and 2.4 ATA for 90 minutes on the other. The most intriguing fact to note is that both methods have been demonstrated to deliver potent outcomes. Regarding the 40 hour hyperbaric protocol, they are substantially the same in terms of frequency of delivery but significantly different in terms of pressure and time:
Using a 40-hour hyperbaric protocol:
- It is generally known that daily HBOT treatments, lasting up to 40 sessions, are the most effective for achieving the full physiological advantages of HBOT.
- Two HBOT sessions a day are not unusual during this programme, which has been widely adopted by many centres and demonstrated to produce excellent clinical results. Note that a minimum 4-hour gap is typically advised between sessions in order to minimise the risk of oxygen poisoning and maintain HBOT’s strong safety records.
- Usually, 5 days straight are advised, followed by a 2-day break.
- With the help of this treatment, it is possible to complete 40 hours of HBOT in one or two months (when applied twice daily). (If only HBOT sessions were conducted every day)

We now have all the factors that can affect the amount of oxygen that will work best for HBOT.